Fumiyo wrote a short review article with Fuminori Tokunaga (Osaka City Univ) describing how defect of linear ubiquitination induced by LUBAC may correlate with human diseases such as autoimmunes and neurodegenerative diseases. We also disucssed potential applications of LUBAC inhibitors.
Tokunaga F, Ikeda F. Linear ubiquitination in immune and neurodegenerative
diseases, and beyond. Biochem Soc Trans. 2022 Mar 28:BST20211078. doi:
10.1042/BST20211078. Epub ahead of print. PMID: 35343567.
