Our review article in JCB is now online!

March 22, 2024

Our review article “The emerging roles of non-canonical ubiquitination in proteostasis and beyond” became open online.

Fumiyo as an editorial board member of the JCB organized and wrote together with Stephanie Kaypee (our postdoc), Fumiaki Ohtake and Yoshino Akizuki (the Ohtake Lab).

The Ohtake lab has expertise in the ubiquitin chains called branched chains. We tried to combine our expertise on linear ubiquitination with theirs in this article.

We believe that we covered the most exciting topics from the ubiquitin biology reserach field.

It was a lot of fun writing this with people with slightly different expertise!


2023年度 卒業お祝いランチの会






New review article on “LUBAC and disease” is out!

Fumiyo wrote  a short review article with Fuminori Tokunaga (Osaka City Univ) describing how defect of linear ubiquitination induced by LUBAC may correlate with human diseases such as autoimmunes and neurodegenerative diseases. We also disucssed potential applications of LUBAC inhibitors.

Tokunaga F, Ikeda F. Linear ubiquitination in immune and neurodegenerative
diseases, and beyond. Biochem Soc Trans. 2022 Mar 28:BST20211078. doi:
10.1042/BST20211078. Epub ahead of print. PMID: 35343567.